Pattern formation by local self‐activation and lateral inhibition
نویسندگان
چکیده
منابع مشابه
Pattern formation by local self-activation and lateral inhibition.
In 1972, we proposed a theory of biological pattern formation in which concentration maxima of pattern forming substances are generated through local self-enhancement in conjunction with long range inhibition. Since then, much evidence in various developmental systems has confirmed the importance of autocatalytic feedback loops combined with inhibitory interaction. Examples are found in the for...
متن کاملRoots: Pattern formation by local self-activation and lateral inhibition
In 1972 we proposed a theory of biological pattern formation in which concentration maxima of pattern forming substances are generated through local selfenhancement in conjunction with long range inhibition. Since then, much evidence in various developmental systems has confirmed the importance of autocatalytic feedback loops combined with inhibitory interaction. Examples are found in the forma...
متن کاملPattern formation by lateral inhibition with feedback: a mathematical model of delta-notch intercellular signalling.
In many developing tissues, adjacent cells diverge in character so as to create a fine-grained pattern of cells in contrasting states of differentiation. It has been proposed that such patterns can be generated through lateral inhibition--a type of cell-cell interaction whereby a cell that adopts a particular fate inhibits its immediate neighbors from doing likewise. Lateral inhibition is well ...
متن کاملApplications of a theory of biological pattern formation based on lateral inhibition.
Model calculations are presented for various problems of development on the basis of a theory of primary pattern formation which we previously proposed. The theory involves shortrange autocatalytic activation and longer-range inhibition (lateral inhibition). When a certain criterion is satisfied, self-regulating patterns are generated. The autocatalytic features of the theory are demonstrated b...
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Individual cellular automata rules are attractive models for a range of biological and physical self-assembling systems. While coexpression and coevolution are common in such systems, ensembles of cellular automata rules remain poorly understood. Here we report the first known analysis of the equally weighted ensemble of all elementary cellular automata (ECA) rules. Ensemble dynamics reveal per...
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ژورنال
عنوان ژورنال: BioEssays
سال: 2000
ISSN: 0265-9247,1521-1878
DOI: 10.1002/1521-1878(200008)22:8<753::aid-bies9>3.3.co;2-q